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Article

Differences in microRNA levels across metabo-endotypes reveal novel insights into asthma heterogeneity.

Respiratory research - 7 Jan 2026

Sharma Rinku, Kelly Rachel S, Mendez Kevin, Chen Qingwen, Hecker Julian, Begum Sofina, Clish Clary, Celedón Juan C, Tantisira Kelan G, Weiss Scott T, Lasky-Su Jessica, McGeachie Michael J

Abstract excerpt

RATIONALE: We previously validated five clinically distinct asthma metabo-endotypes (mechanistically derived asthma subgroups). We hypothesize that metabo-endotype membership may be partially driven by differences in serum microRNA profiles and their influence on metabolite levels. OBJECTIVES: To determine whether serum miRNA levels can help understand the underlying drivers of metabolic dysregulation across...

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Identifiers

PMID: 41501775
DOI: 10.1186/s12931-025-03452-x
PMCID: PMC12869918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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