Enhancing Gene Expression Predictions Using Deep Learning and Functional Annotations.

Abstract excerpt

Transcriptome-wide association studies (TWAS) aim to uncover genotype-phenotype relationships through a two-stage procedure: predicting gene expression from genotypes using an expression quantitative trait locus (eQTL) data set, then testing the predicted expression for trait associations. Accurate gene expression prediction in stage 1 is crucial, as it directly impacts the power to identify associations in stage...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Deep Learning
• Share to Gene Expression
• Share to Genome-Wide Association Study