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Article

Age-related differences in the skeletal phenotype of Brown Norway rats induced to develop chronic kidney disease.

Bone - 1 Sept 2026

Metzger Corinne E, Tak Landon Y, Scorziello Joanna M, Back Lydia A, Matter Emily K, Connerly T Jaymie, O'Neill Kalisha D, Srinivasan Shruthi, Needham Brittany D, Chen Neal X, Moe Sharon M, Allen Matthew R

Abstract excerpt

A large proportion of the chronic kidney disease (CKD) population is over the age of 65 with age being a significant factor increasing fracture incidence in CKD. However, the interactions of aging and CKD on the skeleton remain unclear in part due to limited pre-clinical models to study the intersection of aging and CKD. In the current study, we aimed to define age-related differences in the skeletal...

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PMID: 42128320
DOI: 10.1016/j.bone.2026.117934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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