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Article

Intricacies in arrangement of SNP haplotypes suggest "Great Admixture" that created modern humans.

BMC genomics - 5 Jun 2017

Dutta Rajib, Mainsah Joseph, Yatskiv Yuriy, Chakrabortty Sharmistha, Brennan Patrick, Khuder Basil, Qiu Shuhao, Fedorova Larisa, Fedorov Alexei

Abstract excerpt

BACKGROUND: Inferring history from genomic sequences is challenging and problematic because chromosomes are mosaics of thousands of small Identicalby-descent (IBD) fragments, each of them having their own unique story. However, the main events in recent evolution might be deciphered from comparative analysis of numerous loci. A paradox of why humans, whose effective population size is only 104, have nearly three...

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PMID: 28583085
DOI: 10.1186/s12864-017-3776-5
PMCID: PMC5741169

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