Worldwide human relationships inferred from genome-wide patterns of variation.

doi:10.1126/science.1153717

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Article

Worldwide human relationships inferred from genome-wide patterns of variation.

Science (New York, N.Y.) - 22 Feb 2008

Li Jun Z, Absher Devin M, Tang Hua, Southwick Audrey M, Casto Amanda M, Ramachandran Sohini, Cann Howard M, Barsh Gregory S, Feldman Marcus, Cavalli-Sforza Luigi L, Myers Richard M

Abstract excerpt

Human genetic diversity is shaped by both demographic and biological factors and has fundamental implications for understanding the genetic basis of diseases. We studied 938 unrelated individuals from 51 populations of the Human Genome Diversity Panel at 650,000 common single-nucleotide polymorphism loci. Individual ancestry and population substructure were detectable with very high resolution. The relationship...

Topics

Africa South of the Sahara
Animals
Founder Effect
Gene Frequency
Genetic Drift
Genome, Human
Haplotypes
Heterozygote
Humans
Pan troglodytes
Pedigree
Polymorphism, Single Nucleotide

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PMID: 18292342
DOI: 10.1126/science.1153717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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