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Article

PRPH2/RDS and ROM-1: Historical context, current views and future considerations.

Progress in retinal and eye research - 1 May 2016

Stuck Michael W, Conley Shannon M, Naash Muna I

Abstract excerpt

Peripherin 2 (PRPH2), also known as RDS (retinal degeneration slow) is a photoreceptor specific glycoprotein which is essential for normal photoreceptor health and vision. PRPH2/RDS is necessary for the proper formation of both rod and cone photoreceptor outer segments, the organelle specialized for visual transduction. When PRPH2/RDS is defective or absent, outer segments become disorganized or fail to form...

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Source

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Identifiers

PMID: 26773759
DOI: 10.1016/j.preteyeres.2015.12.002
PMCID: PMC4842342

Genes

PRPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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PRPH2/RDS and ROM-1: Historical context, current views and future considerations.PMID 26773759Read ↗

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A new mouse model for PRPH2 pattern dystrophy exhibits functional compensation prior and subsequent to retinal degeneration.Semantic proximity Read ↗

Prph2 initiates outer segment morphogenesis but maturation requires Prph2/Rom1 oligomerization.Semantic proximity Read ↗

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