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Article

Weight Loss-Induced Metabolic Remodeling in Metabolic dysfunction-associated steatotic liver disease: A Cohort Study Stratified by Genetic Risk.

Clinical nutrition (Edinburgh, Scotland) - 1 Jun 2026

Troisi J, Torre P, Schiavo L, Motta B M, Lombardi M, Festa M, Sarcina T, Masarone M, Persico M

Abstract excerpt

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the hepatic expression of systemic metabolic derangement; however, we have limited understanding of its progression or improvement, and there's a lack of adequate tools to monitor these changes. Metabolomics can provide dynamic biomarkers that reflect pathophysiological change. OBJECTIVE: To describe the effects of weight-loss...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42105611
DOI: 10.1016/j.clnu.2026.106672

Genes

PNPLA3
GCKR
MBOAT7
TM6SF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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