Surgical implications of BRAF V600E-positive Rathke's cleft cysts: prediction of early recurrence based on reclassification to papillary craniopharyngioma.

Abstract excerpt

OBJECTIVE: Rathke's cleft cysts (RCCs) and craniopharyngiomas (CPs) are lesions of the sellar region, both originating from remnants of Rathke's diverticulum. The presence of squamous metaplasia (SM) within RCCs often creates histological overlaps with papillary CPs (PCPs), complicating accurate diagnosis. Given the distinct treatment and clinical outcomes associated with these lesions, precise identification is...

Topics

• Humans
• Craniopharyngioma
• Proto-Oncogene Proteins B-raf
• Central Nervous System Cysts
• Female
• Pituitary Neoplasms