BRAF V600E analysis for the differentiation of papillary craniopharyngiomas and Rathke's cleft cysts.

doi:10.1111/nan.12201

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Article

BRAF V600E analysis for the differentiation of papillary craniopharyngiomas and Rathke's cleft cysts.

Neuropathology and applied neurobiology - 1 Oct 2015

Schweizer Leonille, Capper David, Hölsken Annett, Fahlbusch Rudolf, Flitsch Jörg, Buchfelder Michael, Herold-Mende Christel, von Deimling Andreas, Buslei Rolf

Abstract excerpt

AIMS: The differential diagnosis of cystic epithelial masses of the sellar region, especially the histopathological differentiation of craniopharyngiomas and Rathke's cleft cysts, poses a challenge even to experienced diagnosticians. Recently, BRAF V600E mutations have been described as a genetic...

Topics

Adult
Aged
Antibodies, Monoclonal
Central Nervous System Cysts
Craniopharyngioma
Diagnosis, Differential
Female
Humans
Male
Middle Aged
Mutation
Proto-Oncogene Proteins B-raf
Young Adult

Source

Open in PubMed

Identifiers

PMID: 25442675
DOI: 10.1111/nan.12201

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-25442675-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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