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Article

BRAF V600E analysis for the differentiation of papillary craniopharyngiomas and Rathke's cleft cysts.

Neuropathology and applied neurobiology - 1 Oct 2015

Schweizer Leonille, Capper David, Hölsken Annett, Fahlbusch Rudolf, Flitsch Jörg, Buchfelder Michael, Herold-Mende Christel, von Deimling Andreas, Buslei Rolf

Abstract excerpt

AIMS: The differential diagnosis of cystic epithelial masses of the sellar region, especially the histopathological differentiation of craniopharyngiomas and Rathke's cleft cysts, poses a challenge even to experienced diagnosticians. Recently, BRAF V600E mutations have been described as a genetic hallmark of papillary craniopharyngiomas. We investigated a series of 33 Rathke's cleft cysts to determine the...

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PMID: 25442675
DOI: 10.1111/nan.12201

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BRAF

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