Phenotypic Characterization of Richter Transformation and De Novo Diffuse Large B-Cell Lymphoma With or Without Monoclonal B-Cell Lymphocytosis.

doi:10.1016/j.modpat.2026.101009

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Article

Phenotypic Characterization of Richter Transformation and De Novo Diffuse Large B-Cell Lymphoma With or Without Monoclonal B-Cell Lymphocytosis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2026

Martin-Moro Fernando, Alcoceba Miguel, Romero Samuel, Marquet-Palomanes Juan, Alonso-Castronuño David, Astibia-Mahillo Beatriz, Andreu Rafael, Perez-Alonso Rocio, Rodriguez-Martin Eulalia, De Ramon Cristina, Solano Irene, Martin Garcia-Sancho Alejandro, Piris-Villaespesa Miguel, Blanco Oscar, Roldan-Santiago Ernesto, Garcia-Marco Jose A, Subira Dolores, Navarro-Bailon Almudena, Garcia-Cosio Monica, Garcia-Vela Jose A, Lopez-Jimenez Javier

Abstract excerpt

Richter transformation diffuse large B-cell lymphoma type (DLBCL-RT) is a biologically complex process that requires a comprehensive workup for an accurate diagnosis. Detailed information regarding DLBCL-RT immunophenotype is limited. We used multiparametric flow cytometry and immunohistochemistry to assess the phenotypic profile of 63 patients diagnosed with DLBCL-RT. Cases partially retained the immunophenotype...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42092725
DOI: 10.1016/j.modpat.2026.101009

Genes

CD200
CD38
CD5

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