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Article

Histologic transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma

14 Jul 2016

Abstract excerpt

Although generally considered a clinically indolent neoplasm, CLL/SLL may undergo transformation to a clinically aggressive lymphoma. The most common form of transformation, to DLBCL, is also known as Richter syndrome. Transformation determines the course of the disease and is associated with unfavorable patient outcome. Precise detection of transformation and identification of predictive biomarkers and specific...

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PMID: 27414262
DOI: 10.1002/ajh.24473

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