Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune evasion phenotype is common in Richter transformation diffuse large B-cell lymphoma variant.

Virchows Archiv : an international journal of pathology - 1 Jun 2023

El Hussein Siba, Medeiros L Jeffrey, Gruschkus Stephen K, Wei Peng, Schlette Ellen, Fang Hong, Jelloul Fatima Zahra, Wang Wei, Fiskus Warren, Kanagal-Shamanna Rashmi, Loghavi Sanam, Yang Hong, Li Shaoying, Xu Jie, Tang Zhenya, Thakral Beenu, Jain Nitin, Wierda William G, Patel Keyur, Bhalla Kapil N, Khoury Joseph D

Abstract excerpt

Immune checkpoint inhibitors (PD-1 inhibitors) have shown clinical activity in Richter transformation-diffuse large B-cell lymphoma variant (RT-DLBCL), thus providing for a novel therapeutic approach. The study group consists of 64 patients with RT-DLBCL. Expression of PD-1, PD-L1, CD30, and microsatellite instability (MSI) status (hMLH1, hMSH2, hMSH6, PMS1) was assessed using immunohistochemistry. EBV-encoded...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B7-H1 Antigen
Share to Herpesvirus 4, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune Evasion

Share to Lymphoma, Large B-Cell, Diffuse

Share to Microsatellite Instability

Share to Phenotype

Share to Programmed Cell Death 1 Receptor

Source

Identifiers

PMID: 36864257
DOI: 10.1007/s00428-023-03520-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune evasion phenotype is common in Richter transformation diffuse large B-cell lymphoma variant.PMID 36864257Read ↗

Phenotypic Characterization of Richter Transformation and De Novo Diffuse Large B-Cell Lymphoma With or Without Monoclonal B-Cell Lymphocytosis.Semantic proximity Read ↗

PD-1 Expression in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) and Large B-cell Richter Transformation (DLBCL-RT): A Characteristic Feature of DLBCL-RT and Potential Surrogate Marker for Clonal Relatedness.Semantic proximity Read ↗

PD-L1 gene alterations identify a subset of diffuse large B-cell lymphoma harboring a T-cell–inflamed phenotypeSemantic proximity Read ↗

Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series.Semantic proximity Read ↗

IgVH Mutational Status and Clonality Analysis of Richter's TransformationSemantic proximity Read ↗

Richter Transformation in Chronic Lymphocytic Leukemia: Update in the Era of Novel AgentsSemantic proximity Read ↗

Immune-checkpoint expression in Epstein-Barr virus positive and negative plasmablastic lymphoma: a clinical and pathological study in 82 patients.Semantic proximity Read ↗

Oncogenic Mutations of MYD88 and CD79B in Diffuse Large B-Cell Lymphoma and Implications for Clinical PracticeSemantic proximity Read ↗

Immune Checkpoint Blockade and Biomarkers of Response in Lymphoma: A Case-Illustrated Narrative ReviewSemantic proximity Read ↗

Clinicopathological analysis of programmed cell death 1 and programmed cell death ligand 1 expression in the tumour microenvironments of diffuse large B cell lymphomasSemantic proximity Read ↗

Tumor microenvironment of Burkitt lymphoma: different immune signatures with different clinical behaviorSemantic proximity Read ↗

Primary CNS lymphoma commonly expresses immune response biomarkersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.