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Genomic comparison of clinical strains of Mycobacterium shinjukuense in Japan reveals low diversity and stable genome structures.

Microbial genomics - 1 May 2026

Wada Takayuki, Inoue Hiharu, Yoshida Shiomi, Murase Yoshiro, Igarashi Yuriko, Fukushima Yukari, Nakajima Chie, Suzuki Yasuhiko, Mitarai Satoshi

Abstract excerpt

Mycobacterium shinjukuense, a rare non-tuberculous mycobacterial species closely related to Mycobacterium tuberculosis, remains poorly characterized at the genomic level. To obtain insights into its intraspecies genomic diversity and structure variation, we performed whole-genome sequencing on 18 clinical strains of M. shinjukuense collected from Japan between 2010 and 2017. Phylogenetic analysis revealed limited...

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Identifiers

PMID: 42084611
DOI: 10.1099/mgen.0.001695
PMCID: PMC13143225

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