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Article

Population structure, biogeography and transmissibility of Mycobacterium tuberculosis.

Nature communications - 20 Oct 2021

Freschi Luca, Vargas Roger, Husain Ashaque, Kamal S M Mostofa, Skrahina Alena, Tahseen Sabira, Ismail Nazir, Barbova Anna, Niemann Stefan, Cirillo Daniela Maria, Dean Anna S, Zignol Matteo, Farhat Maha Reda

Abstract excerpt

Mycobacterium tuberculosis is a clonal pathogen proposed to have co-evolved with its human host for millennia, yet our understanding of its genomic diversity and biogeography remains incomplete. Here we use a combination of phylogenetics and dimensionality reduction to reevaluate the population structure of M. tuberculosis, providing an in-depth analysis of the ancient Indo-Oceanic Lineage 1 and the modern...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34671035
DOI: 10.1038/s41467-021-26248-1
PMCID: PMC8528816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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