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Shotgun DNA sequencing for human identification: Dynamic SNP selection and likelihood ratio calculations accounting for errors.

Forensic science international. Genetics - 1 Jan 2025

Andersen Mikkel Meyer, Kampmann Marie-Louise, Jepsen Alberte Honoré, Morling Niels, Eriksen Poul Svante, Børsting Claus, Andersen Jeppe Dyrberg

Abstract excerpt

Shotgun sequencing is a DNA analysis method that potentially determines the nucleotide sequence of every DNA fragment in a sample, unlike PCR-based genotyping methods that is widely used in forensic genetics and targets predefined short tandem repeats (STRs) or predefined single nucleotide polymorphisms (SNPs). Shotgun DNA sequencing is particularly useful for highly degraded low-quality DNA samples, such as...

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PMID: 39270548
DOI: 10.1016/j.fsigen.2024.103146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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