Article
Differentiating between monozygotic twins through next-generation mitochondrial genome sequencing.
Analytical biochemistry - 1 Dec 2015
Wang Zheng, Zhu Ruxin, Zhang Suhua, Bian Yinnan, Lu Daru, Li Chengtao
Abstract excerpt
Monozygotic (MZ) twins, considered to be genetically identical, cannot be distinguished from one another by standard forensic DNA testing. A recent study employed whole genome sequencing to identify extremely rare mutations and reported that mutation analysis could be used to differentiate between MZ twins. Compared with nuclear DNA, mitochondrial DNA (mtDNA) has higher mutation rates; therefore, minor...
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