Article
In Salmonella Typhimurium, YiiD Modulates cAMP Levels in Lag Phase During Growth on Succinate.
Molecular microbiology - 1 Jul 2026
Ciemniecki John A, Will Jessica L, Escalante-Semerena Jorge C
Abstract excerpt
In Salmonella Typhimurium (S. Typhimurium), yiiD encodes a two-domain protein, with one domain having bona fide malonyl-ACP decarboxylase activity, and the other showing sequence similarity to Gcn5-type acetyltransferases (GNATs). Recent work on this enzyme was motivated by the essentiality of its decarboxylase domain to initiation of fatty acid biosynthesis in a strain devoid of β-ketoacyl-[acyl-carrier-protein,...
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