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Article

Regulation of CodY activity through modulation of intracellular branched-chain amino acid pools.

Journal of bacteriology - 1 Dec 2010

Brinsmade Shaun R, Kleijn Roelco J, Sauer Uwe, Sonenshein Abraham L

Abstract excerpt

In several Gram-positive bacterial species, the global transcriptional regulatory protein CodY adjusts the expression of many metabolic genes, apparently in response to changes in the pools of specific metabolites, i.e., the branched-chain amino acids (BCAAs) isoleucine, leucine, and valine (ILV) and the nucleoside triphosphate GTP. CodY not only responds to these metabolites as measured in vitro but also...

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Share to Amino Acids, Branched-Chain
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20935095
DOI: 10.1128/JB.00937-10
PMCID: PMC3008522

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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