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Article

Comparative molecular characterisation of myeloid cathelicidins reveals subspecies-level diversification in indigenous livestock.

Developmental and comparative immunology - 1 Jun 2026

Roy Jini, Panicker Varuna P, Madhavan Vrindha, Uma R, Chinnu M V, Chaithanya K N, Farooq Sulfiya Ummer, Shynu M, Manoj M, Abraham John

Abstract excerpt

Innate immune-related genes are shaped by strong selection pressures due to host-pathogen co-evolution, yet the evolutionary trajectory of cathelicidin antimicrobial (AMP) gene is poorly understood. Despite their central role in innate immunity, the extent of sequence diversification of myeloid cathelicidins across livestock subspecies remains unclear. Present study investigated inter-breed and inter-species...

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PMID: 42070472
DOI: 10.1016/j.dci.2026.105619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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