Genome-wide identification and characterization of β-defensin genes across sixteen Eulipotyphla species: Insights into gene diversification and evolutionary dynamics.

Abstract excerpt

β-defensins, a class of cationic antimicrobial peptides (AMPs), play a crucial role in innate host defense. While these peptides have been extensively studied in vertebrates, their evolutionary history and functional characteristics in Eulipotyphla remain largely unexplored. The order Eulipotyphla, the third largest mammalian order, comprises species that occupy pathogen-rich ecological niches and are known to...

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• beta-Defensins
• Evolution, Molecular
• Gene Duplication
• Genome
• Immunity, Innate