Article
Promoter methylation of APC, P16, and WT1 genes among high-risk HPV infected women of North-Eastern states of India.
Indian journal of medical microbiology - 1 Jan 2026
Dutta Mousumi, Manguri Catherine, Lalrothuama, Taye Milan, Gohain Munmun, Gogoi Gayatri, Das Aseema, Majumdar Tapan, Baidya Jahar Lal, Apum Basumoti, Karlo Bimpi, Singh Kharibam Paikhomba, Sharma Nalini, Lyndoh Clarissa Jane, Kharutso N Azo Louis, Khamo Vinotsole, Grace Pesona, Sarmah Neelanjana, Gogoi Sobnom, Siddique Aktarul Islam, Jakharia Aniruddha, Kaur Harpreet, Borkakoty Biswajyoti
Abstract excerpt
BACKGROUND: Human papillomavirus (HPV) associated cervical cancer is the most prevalent gynaecological malignancy among women globally. Promoter hypermethylation of targeted genes may serve as a novel biomarker to monitor HPV infection dynamics which are likely to progress to HPV related cancers. METHODS: Cervical smear of representative 180 (90 persistent and 90 transient) HPV cases were included in the study...
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