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Genetic variant in LncRNA-NKILA associated with gastric cancer susceptibility and the binding with miR-6731-5p.

Expert review of molecular diagnostics - 1 Aug 2025

Sun Qiuyu, Zhang Ye, Yang Qian, Chen Xiaolin, Wang Yiran, Hou Yuwei, Zhang Yaodong, Wang Kaijuan

Abstract excerpt

BACKGROUND: This study aims to assess the association between lncRNA-NKILA single nucleotide polymorphisms (SNPs) and susceptibility to gastric cancer in the Chinese Han population. RESEARCH DESIGN AND METHODS: Four functional SNPs (rs911157, rs16981280, rs2273534, and rs957313) were validated using bioinformatics analysis and genotyped in 490 patients and 490 controls. A case-control study was conducted to...

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PMID: 40293157
DOI: 10.1080/14737159.2025.2499898

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