Article
Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations.
The Lancet. Oncology - 1 Feb 2020
Lin Guo-Wang, Xu Caigang, Chen Kexin, Huang Hui-Qiang, Chen Jieping, Song Bao, Chan John K C, Li Wenyu, Liu Weiping, Shih Lee-Yung, Chuang Wen-Yu, Kim Won Seog, Tan Wen, Peng Rou-Jun, Laurensia Yurike, Cheah Daryl Ming Zhe, Huang DaChuan, Cheng Chee Leong, Su Yi-Jiun, Tan Soo-Yong, Ng Siok-Bian, Tang Tiffany Pooi Ling, Han Kyudong, Wang Vivien Ya-Fan, Jia Wei-Hua, Pei Zhong, Li Ya-Jun, Gao Song, Shi Yongyong, Hu Zhibin, Zhang Furen, Zhang Ben, Zeng Yi-Xin, Shen Hongbing, He Lin, Ong Choon Kiat, Lim Soon Thye, Chanock Stephen, Kwong Yok-Lam, Lin Dongxin, Rothman Nathaniel, Khor Chiea Chuen, Lan Qing, Bei Jin-Xin
Abstract excerpt
BACKGROUND: Extranodal natural killer T-cell lymphoma (NKTCL; nasal type) is an aggressive malignancy with a particularly high prevalence in Asian and Latin American populations. Epstein-Barr virus infection has a role in the pathogenesis of NKTCL, and HLA-DPB1 variants are risk factors for the disease. We aimed to identify additional novel genetic variants affecting risk of NKTCL. METHODS: We did a genome-wide...
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