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Article

Effects of Isthmus Topography on the Molecular Characteristics of BRAF-mutant Papillary Thyroid Cancer.

Cancer genomics & proteomics - 1 Jan 2026

Kuo Chi-Yu, Cheng Sheena Yi-Hsin, Hsu Yi-Chiung, Cheng Shih-Ping

Abstract excerpt

BACKGROUND/AIM: Previous studies suggest that thyroid cancers in the isthmus are associated with more aggressive behavior and unfavorable patient outcomes compared to lobar tumors. This study aimed to characterize the molecular features of isthmus thyroid cancer. MATERIALS AND METHODS: Transcriptomic and proteomic data were retrieved from the Cancer Genome Atlas. We performed 1:2 propensity score matching based...

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Share to BRAF gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Cancer, Papillary

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Source

Open in PubMed Open full text

Identifiers

PMID: 42055630
DOI: 10.21873/cgp.20585
PMCID: PMC13133813

Genes

BRAF
HAS3
LIF
TNR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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