Article
Role of BRAF and RAS Mutations in Extrathyroidal Extension in Papillary Thyroid Cancer.
Cancer genomics & proteomics - 1 Jan 2000
Park Ji Yeon, Yi Jin Wook, Park Chan Hee, Lim Younggyun, Lee Kye Hwa, Lee Kyu Eun, Kim Ju Han
Abstract excerpt
BACKGROUND/AIM: Extrathyroidal extension (ETE) indicates the invasiveness of primary thyroid tumor into the adjacent tissue, and its importance as a prognostic factor overrides tumor size in classifying the cancer stage. The aim of this study was to determine the molecular basis of ETE in papillary thyroid carcinomas (PTCs). MATERIALS AND METHODS: We systematically defined genes and pathways regulated in ETE...
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