Exploring schizophrenia-associated image-derived digital phenotypes in dual-energy X-ray densitometer scans of non-dominant distal forearm: An explainable machine-learning framework.

Abstract excerpt

Schizophrenia remains diagnosed primarily through clinical assessment, which motivates the researchers to search for quantifiable digital phenotypes. Prior studies suggest that skeletal differences are associated with schizophrenia, leading us to explore whether bone structure might contain detectable disease-related digital signals. To investigate this possibility, we developed an end-to-end framework for...

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