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Article

Discovering the gene-brain-behavior link in autism via generative machine learning.

Science advances - 14 Jun 2024

Kundu Shinjini, Sair Haris, Sherr Elliott H, Mukherjee Pratik, Rohde Gustavo K

Abstract excerpt

Autism is traditionally diagnosed behaviorally but has a strong genetic basis. A genetics-first approach could transform understanding and treatment of autism. However, isolating the gene-brain-behavior relationship from confounding sources of variability is a challenge. We demonstrate a novel technique, 3D transport-based morphometry (TBM), to extract the structural brain changes linked to genetic copy number...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38865470
DOI: 10.1126/sciadv.adl5307
PMCID: PMC11168471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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