Article
End-stage valvular heart disease requiring heart transplantation: risk profile, surgical modifiers, and myocardial pathology.
BMC cardiovascular disorders - 28 Apr 2026
Wang Yifan, Zhao Yiqi, Wang Weiteng, Jia Hao, Chen Xiao, Mo Han, Sun Zhe, Wang Xiaohu, Shu Songren, Shi Hongjie, Luo Zhiling, Hua Xiumeng, Cui Hao, Song Jiangping
Abstract excerpt
BACKGROUND: End-stage valvular heart disease (VHD) constitutes a small but high-risk subset of heart transplant (HTx) recipients, and data describing their natural history and determinants of progression to HTx are limited. We aimed to characterize the clinical, genetic, surgical, and pathological substrates of patients undergoing HTx for end-stage VHD and to assess whether timely cardiac valvular surgery (CVS)...
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