Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular Landscapes of Nondiseased Human Cardiac Valves From End-Stage Heart Failure–Explanted Heart

6 Oct 2022

Abstract excerpt

BACKGROUND: Exploring the mechanisms of valvular heart disease at the cellular level may be useful to identify new therapeutic targets; however, the comprehensive cellular landscape of nondiseased human cardiac valve leaflets remains unclear. METHODS: The cellular landscapes of nondiseased human cardiac valve leaflets (5 aortic valves, 5 pulmonary valves, 5 tricuspid valves, and 3 mitral valves) from end-stage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac Valve Diseases and Treatments
Share to Congenital heart defects research
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36200446
DOI: 10.1161/atvbaha.122.318314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cellular Landscapes of Nondiseased Human Cardiac Valves From End-Stage Heart Failure–Explanted HeartPMID 36200446Read ↗

Cell-Type Transcriptome Atlas of Human Aortic Valves Reveal Cell Heterogeneity and Endothelial to Mesenchymal Transition Involved in Calcific Aortic Valve Disease.Semantic proximity Read ↗

Advances in single-cell transcriptomics: unraveling the pathogenesis of calcific aortic valve disease.Semantic proximity Read ↗

Side- and Disease-Dependent Changes in Human Aortic Valve Cell Population and Transcriptomic Heterogeneity Determined by Single-Cell RNA SequencingSemantic proximity Read ↗

Single-cell transcriptomics reveals cellular heterogeneity and macrophage-to-mesenchymal transition in bicuspid calcific aortic valve diseaseSemantic proximity Read ↗

Harnessing Single-Cell RNA Sequencing to Better Understand How Diseased Cells Behave the Way They Do in Cardiovascular Disease.Semantic proximity Read ↗

Cells and gene expression programs in the adult human heartSemantic proximity Read ↗

A human cell model of cardiac pathophysiological valvulogenesisSemantic proximity Read ↗

A disease-driver population within interstitial cells of human calcific aortic valves identified via single-cell and proteomic profilingSemantic proximity Read ↗

Dynamic Heterogeneity of the Heart Valve Interstitial Cell Population in Mitral Valve Health and DiseaseSemantic proximity Read ↗

Single cell transcriptional profiling reveals cellular diversity, communication, and sexual dimorphism in the mouse heartSemantic proximity Read ↗

Cell-cell interactions in the heart: advanced cardiac models and omics technologiesSemantic proximity Read ↗

Single-cell transcriptomics reveals cell-type-specific diversification in human heart failureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.