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Article

Dilated cardiomyopathy caused by truncating titin variants: long-term outcomes, arrhythmias, response to treatment and sex differences.

Journal of medical genetics - 1 Dec 2021

Vissing Christoffer Rasmus, Rasmussen Torsten Bloch, Dybro Anne Mette, Olesen Morten Salling, Pedersen Lisbeth Nørum, Jensen Morten, Bundgaard Henning, Christensen Alex Hørby

Abstract excerpt

BACKGROUND: Truncating variants in titin (TTNtv) are the most common cause of dilated cardiomyopathy (DCM). We evaluated the genotype-phenotype correlation in TTNtv-DCM, with a special focus on long-term outcomes, arrhythmias, response to treatment and sex-related presentation. METHODS: Data on patient characteristics and outcomes were collected retrospectively from electronic health records of patients genotyped...

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Identifiers

PMID: 33106378
DOI: 10.1136/jmedgenet-2020-107178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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