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Article

Phenotypic Diversity and Outcomes of Transcatheter Mitral Repair for Secondary Mitral Regurgitation: Insights From the COAPT and MITRA-FR Trials.

JACC. Cardiovascular interventions - 11 May 2026

Bonnet Guillaume, Rommel Karl-Philipp, Redfors Bjorn, Le Ruz Robin, Lachmann Mark, Alu Maria C, Iung Bernard, Gertz Zachary M, Modine Thomas, Abraham William T, Mewton Nathan, Lindenfeld Joann, Messika-Zeitoun David, Mack Michael J, Obadia Jean Francois, Stone Gregg W, Granada Juan F

Abstract excerpt

BACKGROUND: Mitral valve transcatheter edge-to-edge repair (M-TEER) is effective for treating patients with secondary mitral regurgitation (SMR), but therapeutic response varies because of anatomy and patient heterogeneity. OBJECTIVES: The aim of this study was to identify distinct SMR phenotypes and analyze their response to M-TEER in the COAPT (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous...

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PMID: 42120116
DOI: 10.1016/j.jcin.2026.02.030

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