Utilization of HLA-B27 genotyping in a mixed primary-hospital care (2023-2025): Test yield by requesting service, demographic predictors, and prevention of unnecessary duplicate genetic testing.

Abstract excerpt

BACKGROUND: HLA-B27 is a constitutional genetic marker strongly associated with spondyloarthritis and HLA-B27-associated acute anterior uveitis; its diagnostic value depends on clinical context and pre-test probability. For "once-in-a-lifetime" constitutional genetic tests, repeat testing rarely adds clinical value and is a target for laboratory stewardship. METHODS: Retrospective observational study of all...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Aged
• Share to Genetic Testing