Article
Possible Association of IFN-γ Gene -316A/G SNP with Humoral Immune Response to Killed H5N1 HPAI Vaccine in a Red Junglefowl Population.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Nov 2015
Ji Bin, Sun Ting-Ting, Ma Zhi-Liang, Lu Qiong-Fen, Hu Wen-Li, Jian Zong-Hui, Jiang Yu, Chen Pei-Fu
Abstract excerpt
To understand the role of interferon (IFN)-γ gene (IFNG) single-nucleotide polymorphisms (SNPs) in the resistance to H5N1 highly pathogenic avian influenza (HPAI), we determined the SNPs, the log2-transformed specific antibody titers, and ex vivo recall antigen-specific IFN-γ production by peripheral blood mononuclear cells (PBMCs) in 62 red junglefowls (Gallus gallus) immunized twice with inactivated H5N1 HPAI...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
