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Article

Phenotypes and personalized medicine in the acute respiratory distress syndrome.

Intensive care medicine - 1 Dec 2020

Matthay Michael A, Arabi Yaseen M, Siegel Emily R, Ware Lorraine B, Bos Lieuwe D J, Sinha Pratik, Beitler Jeremy R, Wick Katherine D, Curley Martha A Q, Constantin Jean-Michel, Levitt Joseph E, Calfee Carolyn S

Abstract excerpt

Although the acute respiratory distress syndrome (ARDS) is well defined by the development of acute hypoxemia, bilateral infiltrates and non-cardiogenic pulmonary edema, ARDS is heterogeneous in terms of clinical risk factors, physiology of lung injury, microbiology, and biology, potentially explaining why pharmacologic therapies have been mostly unsuccessful in treating ARDS. Identifying phenotypes of ARDS and...

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Identifiers

PMID: 33206201
DOI: 10.1007/s00134-020-06296-9
PMCID: PMC7673253

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