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Article

Novel dual regulatory roles of RpoA in quorum sensing regulation and social behavior switching in Pseudomonas aeruginosa.

mBio - 13 May 2026

Chen Huali, Liang Yonglin, Zhou Xiaoqing, Cai Wenjie, Qiu Huifang, Dandekar Ajai A, Dai Weijun

Abstract excerpt

Understanding the social structure and evolutionary dynamics of microbial communities requires the identification and characterization of relevant mutant subpopulations. While Pseudomonas aeruginosa employs quorum sensing (QS) to coordinate population-wide behaviors, the social traits of many QS mutants remain poorly defined. In this study, we developed an iterative "targeted gene duplication followed by mutant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41874170
DOI: 10.1128/mbio.00032-26
PMCID: PMC13170360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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