Collaboration between a temperate phage and Pseudomonas aeruginosa quorum sensing constrains social cheats.

Abstract excerpt

Pseudomonas aeruginosa uses quorum sensing (QS) to coordinate cooperative behaviors. In the model strain PAO1, QS activates dozens of genes, including those for cyanide production and cyanide resistance. The induction of cyanide synthesis and resistance mechanisms serves to constrain the emergence of QS mutants. Strain CI27 does not possess the cyanide synthesis genes. Here, we ask if this isolate can constrain...

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