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MTHFR C677T and A1298C Gene Variants in Patients with Turner Syndrome and Their Mothers.

Genetic testing and molecular biomarkers - 1 May 2026

Rios-Flores Izabel Maryalexandra, Flores-Contreras Lucía, Bobadilla-Morales Lucina, Corona-Rivera Alfredo, Brukman-Jiménez Sinhué Alejandro, Cuero-Quezada Idalid, Claro-Marín Alexandra María, Corona-Rivera Jorge Román

Abstract excerpt

BACKGROUND: It has been proposed that there is a relationship between chromosomal nondisjunction and folate metabolism. Previous studies in mothers of girls with Turner syndrome (TS) and TS patients have suggested that 5,10-methylentetrahydrofolate reductase (MTHFR) C677T and A1298C gene variants might contribute to the risk of TS. However, data in different populations have yielded contradictory results. AIM:...

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PMID: 42003847
DOI: 10.1177/19450265261444629

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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