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Article

Methylenetetrahydrofolate reductase gene polymorphisms in Egyptian Turner Syndrome patients.

Acta biochimica Polonica - 1 Jan 2015

Ismail Manal F, Zarouk Waheba A, Ruby Mona O, Mahmoud Wael M, Gad Randa S

Abstract excerpt

BACKGROUND: Folate metabolism dysfunctions can result in DNA hypomethylation and abnormal chromosome segregation. Two common polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) encoding gene (C677T and A1298C) reduce MTHFR activity, but when associated with aneuploidy, the results are conflicting. Turner Syndrome (TS) is an interesting model for investigating the association between MTHFR gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26217949
DOI: 10.18388/abp.2015_974

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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