Article
Biophysical characterization of an engineered recombinant Zeocin Binding Protein (ZBP) mutant.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy - 5 Oct 2026
Malik Ajamaluddin, Alharbi Sara, Alamri Abdulaziz, Khan Javed Masood, Khan Mohd Shahnawaz, Alhomida Abdullah, Ahmad Tauseef
Abstract excerpt
Traditional strategies for identifying molecular chaperones are often indirect and nonspecific, such as monitoring stress-induced changes in gene expression or assessing in vitro chaperone activity, which are labor-intensive and may yield false-negative results. To overcome these challenges, we engineered a Zeocin Binding Protein (ZBP) variant, P9E, as a biosensor for protein folding and stability in vivo. ZBP...
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