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Article

Identifying the Best Predictive Biomarker in Pharmacogenomics Through Multiple Comparisons With the Best.

Biometrical journal. Biometrische Zeitschrift - 1 Apr 2026

Zhai Song, Shen Judong, Hsu Jason C, Cui Xinping

Abstract excerpt

Single gene mutations are increasingly being adopted as clinical biomarkers for the optimal application of various therapeutic areas (such as cancer and cardiovascular disease). A single nucleotide polymorphism (SNP), the most common type of genetic variation in human populations, can affect the abundance and function of gene products at the molecular level. In practice, a single-predictor model is usually built...

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PMID: 41987500
DOI: 10.1002/bimj.70130
PMCID: PMC13084167

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