Article
Identifying optimal biomarker combinations for treatment selection via a robust kernel method.
Biometrics - 1 Dec 2014
Huang Ying, Fong Youyi
Abstract excerpt
Treatment-selection markers predict an individual's response to different therapies, thus allowing for the selection of a therapy with the best predicted outcome. A good marker-based treatment-selection rule can significantly impact public health through the reduction of the disease burden in a cost-effective manner. Our goal in this article is to use data from randomized trials to identify optimal linear and...
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