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Article

Selecting predictive biomarkers from genomic data.

PloS one - 1 Jan 2022

Frommlet Florian, Szulc Piotr, König Franz, Bogdan Malgorzata

Abstract excerpt

Recently there have been tremendous efforts to develop statistical procedures which allow to determine subgroups of patients for which certain treatments are effective. This article focuses on the selection of prognostic and predictive genetic biomarkers based on a relatively large number of candidate Single Nucleotide Polymorphisms (SNPs). We consider models which include prognostic markers as main effects and...

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PMID: 35709188
DOI: 10.1371/journal.pone.0269369
PMCID: PMC9202896

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