Genetic association analysis of lnc-AMFR-1:1 rs4784659 C > T and neuroblastoma susceptibility in Chinese pediatric patients.

doi:10.1007/s00383-026-06426-2

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Genetic association analysis of lnc-AMFR-1:1 rs4784659 C > T and neuroblastoma susceptibility in Chinese pediatric patients.

Pediatric surgery international - 15 Apr 2026

Feng Tianli, Su Yuling, Zhou Chunlei, Zhang Xinxin, Liu Jiabin, Zhang Wenli, He Jing, Huang Xinjiang

Abstract excerpt

BACKGROUND: Neuroblastoma, a neuroendocrine tumor of the sympathetic ganglia, is the leading solid extracranial malignancy in children. The lnc-AMFR-1:1 rs4784659 polymorphism in long noncoding RNA (lncRNA) has been reported to be associated with susceptibility to several cancers, but its role in neuroblastoma remains unclear. METHODS: We studied 402 patients with neuroblastoma and 473 cancer-free controls from...

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PMID: 41984207
DOI: 10.1007/s00383-026-06426-2

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