Article
RTEL1 gene polymorphisms and neuroblastoma risk in Chinese children.
BMC cancer - 24 Nov 2023
Zhang Ting, Zhou Chunlei, Guo Jiejie, Chang Jiamin, Wu Haiyan, He Jing
Abstract excerpt
BACKGROUND: Neuroblastoma, a neuroendocrine tumor originating from the sympathetic ganglia, is one of the most common malignancies in childhood. RTEL1 is critical in many fundamental cellular processes, such as DNA replication, DNA damage repair, genomic integrity, and telomere stability. Single nucleotide polymorphisms (SNPs) in the RTEL1 gene have been reported to confer susceptibility to multiple cancers, but...
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