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High Frequencies of Phenotypically and Functionally Senescent and Exhausted CD56 + CD57 + PD-1 + Natural Killer Cells, SARS-CoV-2-Specific Memory CD4 + and CD8 + T cells Associated with Severe Disease in Unvaccinated COVID-19 Patients

2022-07-27

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<h4>ABSTRACT</h4> Unvaccinated COVID-19 patients display a large spectrum of symptoms, ranging from asymptomatic to severe symptoms, the latter even causing death. Distinct Natural killer (NK) and CD4 + and CD8 + T cells immune responses are generated in COVID-19 patients. However, the phenotype and functional characteristics of NK cells and T-cells associated with COVID-19 pathogenesis versus protection remain...

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Literature Corpus work: 98019046-18c2-58ee-abd0-5a15cbc874f1
DOI: 10.1101/2022.07.26.501655

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High Frequencies of Phenotypically and Functionally Senescent and Exhausted CD56 + CD57 + PD-1 + Natural Killer Cells, SARS-CoV-2-Specific Memory CD4 + and CD8 + T cells Associated with Severe Disease in Unvaccinated COVID-19 PatientsDOI 10.1101/2022.07.26.501655Read

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High Frequencies of Phenotypically and Functionally Senescent and Exhausted CD56 <sup>+</sup> CD57 <sup>+</sup> PD-1 <sup>+</sup> Natural Killer Cells, SARS-CoV-2-Specific Memory CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells Associated with Severe Disease in Unvaccinated COVID-19 Patients

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