Article
Integrating Vascular Phenotypic and Proteomic Analysis in an Open Microfluidic Platform.
ACS nano - 10 Sept 2024
Jung Sangmin, Cheong Sunghun, Lee Yoonho, Lee Jungseub, Lee Jihye, Kwon Min-Seok, Oh Young Sun, Kim Taewan, Ha Sungjae, Kim Sung Jae, Jo Dong Hyun, Ko Jihoon, Jeon Noo Li
Abstract excerpt
This research introduces a vascular phenotypic and proteomic analysis (VPT) platform designed to perform high-throughput experiments on vascular development. The VPT platform utilizes an open-channel configuration that facilitates angiogenesis by precise alignment of endothelial cells, allowing for a 3D morphological examination and protein analysis. We study the effects of antiangiogenic agents─bevacizumab,...
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