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Article

Nuclear basket subunits Nup211 and Rsm1 influence RNA 3'-processing and transcription termination in fission yeast.

RNA (New York, N.Y.) - 16 Jun 2026

Bednor Lauren, Innokentev Aleksei, Sanchez Ana M, Sem Angela, Schwer Beate, Shuman Stewart

Abstract excerpt

The fission yeast phosphate acquisition (PHO) regulon is repressed under phosphate-replete conditions by upstream lncRNA-mediated transcriptional interference. Inositol-1-pyrophosphates control PHO gene expression via their action as agonists of precocious PHO lncRNA 3'-processing/termination. Inositol pyrophosphatase-inactivating asp1-STF mutations that increase inositol-1-pyrophosphates elicit derepression of...

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PMID: 41974504
DOI: 10.1261/rna.081007.126

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