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Article

Poly(A) site choice and Pol2 CTD Serine-5 status govern lncRNA control of phosphate-responsive tgp1 gene expression in fission yeast.

RNA (New York, N.Y.) - 1 Feb 2018

Sanchez Ana M, Shuman Stewart, Schwer Beate

Abstract excerpt

Expression of fission yeast glycerophosphate transporter Tgp1 is repressed in phosphate-rich medium and induced during phosphate starvation. Repression is enforced by transcription of the nc-tgp1 locus upstream of tgp1 to produce a long noncoding (lnc) RNA. Here we identify two essential elements of the nc-tgp1 promoter: a TATA box -30TATATATA-23 and a HomolD box -64CAGTCACA-57, mutations of which inactivate the...

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Share to Phosphates
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29122971
DOI: 10.1261/rna.063966.117
PMCID: PMC5769750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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