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Article

Associations of polygenic risk scores for type 2 diabetes with metabolic measures in Pacific Islanders from Guam and Saipan.

Journal of human genetics - 1 Aug 2026

Ramirez-Luzuriaga Maria J, Safabakhsh Saied, Salehi Rasol, Kobes Sayuko, Aflague Tanisha F, Duenas Sarmiento Jenny, Curran Joanne E, Nelson Robert G, Curtis Jeffrey M, Moffett Carol D, Hsueh Wen-Chi, Hanson Robert L

Abstract excerpt

Several polygenic risk scores (PRSs) for type 2 diabetes (T2D) have been derived from genome-wide association studies (GWASs), but Pacific populations have generally not been represented in these GWASs. The aim of this study was to examine the association of PRS for T2D with diabetes and clinical measures in Pacific Islander populations from Guam and Saipan. We analyzed seven constructions of PRSs in 1990...

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Share to Blood Glucose
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41951760
DOI: 10.1038/s10038-026-01474-x
PMCID: PMC13400312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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