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Article

Association of Genetic Predisposition and Physical Activity With Risk of Gestational Diabetes in Nulliparous Women.

JAMA network open - 1 Aug 2022

Pagel Kymberleigh A, Chu Hoyin, Ramola Rashika, Guerrero Rafael F, Chung Judith H, Parry Samuel, Reddy Uma M, Silver Robert M, Steller Jonathan G, Yee Lynn M, Wapner Ronald J, Hahn Matthew W, Natarajan Sriraam, Haas David M, Radivojac Predrag

Abstract excerpt

Importance: Polygenic risk scores (PRS) for type 2 diabetes (T2D) can improve risk prediction for gestational diabetes (GD), yet the strength of the association between genetic and lifestyle risk factors has not been quantified. Objective: To assess the association of PRS and physical activity in existing GD risk models and identify patient subgroups who may receive the most benefits from a PRS or physical...

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Source

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Identifiers

PMID: 36040739
DOI: 10.1001/jamanetworkopen.2022.29158
PMCID: PMC9428742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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